Products
Willin antibody
- Product Name
- Willin antibody
- Catalogue No.
- FNab09510
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- FERM domain containing 6
- Alternative Names
- EX1 antibody, FERM domain containing 6 antibody, FRMD6 antibody, Willin antibody
- UniProt ID
- Q96NE9
- Observed MW
- 72 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
Recombinant proteins were subjected to SDS PAGE followed by western blot with FNab09510(Willin Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab09510(Willin antibody) at dilution of 1:50
- Background
- Willin, also known as FRMD6 or human Expanded(hEx), is a member of the FERM-domain family of cytoskeletal crosslinkers. It is a potent inhibitor of cell proliferation, transformation and modulator of drug sensitivity, suggesting it possesses tumor suppressor properties. Willin is widely expressed in normal tissues. Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors.This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.
