Products
WAPL; WAPAL antibody
- Product Name
- WAPL; WAPAL antibody
- Catalogue No.
- FNab09467
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- wings apart-like homolog(Drosophila)
- Alternative Names
- FOE antibody, Friend of EBNA2 protein antibody, KIAA0261 antibody, WAPAL antibody, WAPL antibody
- UniProt ID
- Q7Z5K2
- Observed MW
- 140 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab09467(WAPL; WAPAL antibody) at dilution of 1:300
- Background
- The wings apart-like(WAPL, or WAPAL) protein was originally identified as a gene product that potentially regulates heterochromatin organization in Drosophila melanogaster. Human WAPL is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Overexpression of WAPL disturbs mitosis and cytokinesis, and contributes to tumor progression by induction of chromosomal instability.
