VPS54 antibody

Synonyms:HCC8 antibody, hVps54L antibody, SLP 8p antibody, Tumor antigen HOM HCC 8 antibody, Tumor antigen SLP 8p antibody, VPS54 antibody, VPS54L antibody
Catalogue No.:FNab09449Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
VPS54 antibody
Catalogue No.
FNab09449
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
vacuolar protein sorting 54 homolog
Alternative Names
HCC8 antibody, hVps54L antibody, SLP 8p antibody, Tumor antigen HOM HCC 8 antibody, Tumor antigen SLP 8p antibody, VPS54 antibody, VPS54L antibody
UniProt ID
Q9P1Q0
Observed MW
111 kDa
Application
Tested Applications
ELISA, WB, IP
Recommended dilution
WB: 1:500-1:5000;IP: 1:200-1:2000
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab09449(VPS54 antibody) at dilution of 1:300
IP Result of anti-VPS54 (IP:FNab09449, 4ug; Detection:FNab09449 1:300) with mouse brain tissue lysate 4000ug.
Background
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:18367545). Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling(PubMed:25799061).