Products
VPS52 antibody
- Product Name
- VPS52 antibody
- Catalogue No.
- FNab09447
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- vacuolar protein sorting 52 homolog
- Alternative Names
- ARE1 antibody, dJ1033B10.5 antibody, DKFZp547I194 antibody, RP5 1033B10 antibody, SAC2 antibody, SACM2L antibody, VPS52 antibody
- UniProt ID
- Q8N1B4
- Observed MW
- 82 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:200-1:2000；IP: 1:500-1:5000；IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
mouse skin tissue were subjected to SDS PAGE followed by western blot with FNab09447(VPS52 antibody) at dilution of 1:1000
IP Result of anti-VPS52 (IP:FNab09447, 3ug; Detection:FNab09447 1:1000) with mouse skin tissue lysate 3200ug.
Immunohistochemistry of paraffin-embedded human gliomas using FNab09447(VPS52 antibody) at dilution of 1:50
- Background
- Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061).
