Products
VPS33B antibody
- Product Name
- VPS33B antibody
- Catalogue No.
- FNab09436
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- vacuolar protein sorting 33 homolog B(yeast)
- Alternative Names
- FLJ14848 antibody, hVPS33B antibody, VPS33B antibody
- UniProt ID
- Q9H267
- Observed MW
- 71 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab09436(VPS33B antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human kidney using FNab09436(VPS33B antibody) at dilution of 1:100
- Background
- May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages(PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity(PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies(MVBs) promoting MVBs maturation in megakaryocytes(By similarity).
