Products
VPS25 antibody
- Product Name
- VPS25 antibody
- Catalogue No.
- FNab09431
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- vacuolar protein sorting 25 homolog
- Alternative Names
- DERP9 antibody, EAP20 antibody, ESCRT II complex subunit VPS25 antibody, FAP20 antibody, hVps25 antibody, VPS25 antibody
- UniProt ID
- Q9BRG1
- Observed MW
- 21 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09431(VPS25 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09431(VPS25 antibody) at dilution of 1:50
- Background
- Component of the ESCRT-II complex(endosomal sorting complex required for transport II), which is required for multivesicular body(MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
