Products
VMAT2 antibody
- Product Name
- VMAT2 antibody
- Catalogue No.
- FNab09418
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- solute carrier family 18(vesicular monoamine), member 2
- Alternative Names
- Monoamine transporter antibody, SLC18A2 antibody, SVAT antibody, SVMT antibody, VAT2 antibody, Vesicular amine transporter 2 antibody, VMAT2 antibody
- UniProt ID
- Q05940
- Observed MW
- 56 kDa, 66 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09418(VMAT2 antibody) at dilution of 1:300
- Background
- VMAT2 is a vesicular monoamine transporter that is responsible for the uptake and storage of monoamines(dopaine, norepinephrine, epinephrine, histamine and serotonin) in neurons, endocrine cells, and tumors deriving from these cells. Histamine-producing endocrine tumors(gastric carcinoids) expressed VMAT2 almost exclusively, thus VMAT2 is useful in classification of neuroendocrine tumors. Reduced expression of VMAT2 has often been observed in Parkinson’s diseased(PD) brain, and detection of VMAT2 can be used to reflect the dopamine neuron loss and predict the disease process. VMAT2 migrated as a major band of 65-75 kDa and a minor band of 55-60 kDa, representing the glycosylated form and native form.
