Products
Villin antibody
- Product Name
- Villin antibody
- Catalogue No.
- FNab09406
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- villin 1
- Alternative Names
- VIL antibody, VIL1 antibody, Villin antibody, villin 1 antibody
- UniProt ID
- P09327
- Observed MW
- 93 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:1000-1:10000; IHC: 1:50-1:8000; IF: 1:20-1:200; IP: 1:200-1:1000
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab09406(VIL1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab09406(VIL1 Antibody) at dilution of 1:200
- Background
- Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
