HeLa cells were subjected to SDS PAGE followed by western blot with FNab09378(VAV2 antibody) at dilution of 1:1000
IP Result of anti-VAV2 (IP:FNab09378, 4ug; Detection:FNab09378 1:1000) with HeLa cells lysate 2500ug.
Immunohistochemistry of paraffin-embedded human pancreas using FNab09378(VAV2 antibody) at dilution of 1:50
Background
Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly(By similarity).