Products
VASP antibody
- Product Name
- VASP antibody
- Catalogue No.
- FNab09375
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- vasodilator-stimulated phosphoprotein
- Alternative Names
- VASP antibody
- UniProt ID
- P50552
- Observed MW
- 46 kDa, 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, FC, IP
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200；IF: 1:20-1:200; IP: 1:200-1:2000
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab09375(VASP antibody) at dilution of 1:1000
IP Result of anti-VASP (IP:FNab09375, 4ug; Detection:FNab09375 1:500) with mouse spleen tissue lysate 4800ug.
Immunohistochemistry of paraffin-embedded human testis using FNab09375(VASP antibody) at dilution of 1:100
- Background
- Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
