Products
VAPA antibody
- Product Name
- VAPA antibody
- Catalogue No.
- FNab09369
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- VAMP(vesicle-associated membrane protein)-associated protein A, 33kDa
- Alternative Names
- 33 kDa VAMP associated protein antibody, hVAP 33 antibody, VAMP A antibody, VAMP associated protein A antibody, VAP 33 antibody, VAP A antibody, VAP33 antibody, VAPA antibody
- UniProt ID
- Q9P0L0
- Observed MW
- 33 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:50-1:200；IF: 1:10-1:100; IP: 1:500-1:5000
Validated Images
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab09369(VAPA antibody) at dilution of 1:500
IP Result of anti-VAPA (IP:FNab09369, 3ug; Detection:FNab09369 1:1000) with HEK-293 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded human colon cancer using FNab09369(VAPA antibody) at dilution of 1:100
- Background
- Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:25447204). With OSBPL3, may regulate ER morphology(PubMed:16143324). May play a role in vesicle trafficking(PubMed:11511104, PubMed:19289470).
