Products
USP49 antibody
- Product Name
- USP49 antibody
- Catalogue No.
- FNab09338
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 49
- Alternative Names
- Deubiquitinating enzyme 49 antibody, Ubiquitin thiolesterase 49 antibody, USP49 antibody
- UniProt ID
- Q70CQ1
- Observed MW
- 73 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1：20-1：200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab09338(USP49 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab09338(USP49 antibody) at dilution of 1:50
- Background
- Specifically deubiquitinates histone H2B at 'Lys-120'(H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
