Products
USP37 antibody
- Product Name
- USP37 antibody
- Catalogue No.
- FNab09330
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 37
- Alternative Names
- Deubiquitinating enzyme 37 antibody, KIAA1594 antibody, Ubiquitin thiolesterase 37 antibody, USP37 antibody
- UniProt ID
- Q86T82
- Observed MW
- 110 kDa,70 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000; IP: 1：200-1：2000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09330(USP37 antibody) at dilution of 1:500
- Background
- Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).
