Products
USP34 antibody
- Product Name
- USP34 antibody
- Catalogue No.
- FNab09327
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 34
- Alternative Names
- Deubiquitinating enzyme 34 antibody, FLJ43910 antibody, KIAA0570 antibody, KIAA0729 antibody, Ubiquitin thiolesterase 34 antibody, USP34 antibody
- UniProt ID
- Q70CQ2
- Observed MW
- 47 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IP: 1：200-1：2000; IHC: 1：20-1：200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab09327(USP34 antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09327(USP34 Antibody) at dilution of 1:50
- Background
- Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
