K-562 cells were subjected to SDS PAGE followed by western blot with FNab09323(USP3 antibody) at dilution of 1:500
Background
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response(DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.