Products
USP18 antibody
- Product Name
- USP18 antibody
- Catalogue No.
- FNab09313
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 18
- Alternative Names
- 43 kDa ISG15 specific protease antibody, hUBP43 antibody, ISG43 antibody, Ubl thiolesterase 18 antibody, UBP43 antibody, USP18 antibody
- UniProt ID
- Q9UMW8
- Observed MW
- 70 kDa, 43 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:1000
Validated Images
WB result of USP18 antibody(FNab09313) with MCF-7 cells .
- Background
- Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.Isoform 2: Has enzymatic activity similar to isoform 1 and interferes with type I interferon signaling. Major deISGylation enzyme for nuclear proteins(PubMed:22170061).
