Uroguanylin antibody

Synonyms:GCAP II antibody, GCAP II Uroguanylin antibody, Guanylate cyclase activator 2B antibody, GUCA2B antibody, UGN antibody
Catalogue No.:FNab09293Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Uroguanylin antibody
Catalogue No.
FNab09293
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
guanylate cyclase activator 2B(uroguanylin)
Alternative Names
GCAP II antibody, GCAP II Uroguanylin antibody, Guanylate cyclase activator 2B antibody, GUCA2B antibody, UGN antibody
UniProt ID
Q16661
Observed MW
12 kDa
Application
Tested Applications
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF:1:20-1:200
Validated Images
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab09293(Uroguanylin antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab09293(Uroguanylin antibody) at dilution of 1:50
Background
Uroguanylin, also named as GUCA2B, is a candidate intestinal natriuretic hormone that controls the sodium and water balance between the intestine and the kidneys. It has been reported that the uroguanylin knockout mouse exhibits elevated blood pressure. Therefore, the GUCA2B gene is thought to be a susceptibility gene for essential hypertension(EH).