mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab09293(Uroguanylin antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab09293(Uroguanylin antibody) at dilution of 1:50
Background
Uroguanylin, also named as GUCA2B, is a candidate intestinal natriuretic hormone that controls the sodium and water balance between the intestine and the kidneys. It has been reported that the uroguanylin knockout mouse exhibits elevated blood pressure. Therefore, the GUCA2B gene is thought to be a susceptibility gene for essential hypertension(EH).