Products
UNC5D-Specific antibody
- Product Name
- UNC5D-Specific antibody
- Catalogue No.
- FNab09264
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- unc-5 homolog D(C. elegans)
- Alternative Names
- UNC5D antibody, Protein unc 5 homolog D antibody, FLJ16019 antibody, KIAA1777 antibody, Netrin receptor UNC5D antibody
- UniProt ID
- Q6UXZ4
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:2000
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab09264(UNC5D-Specific antibody) at dilution of 1:500
- Background
- UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5D.
