Products
UNC5C-Specific antibody
- Product Name
- UNC5C-Specific antibody
- Catalogue No.
- FNab09263
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- unc-5 homolog C(C. elegans)
- Alternative Names
- UNC5C antibody, unc 5 homolog C(C. elegans) antibody, UNC5H3 antibody, Protein unc 5 homolog 3 antibody, Protein unc 5 homolog C antibody
- UniProt ID
- O95185
- Observed MW
- 103 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09263(UNC5C-Specific antibody) at dilution of 1:1000
- Background
- UNC5C, also named as UNC5H3, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5C.
