Products
ULK1 antibody
- Product Name
- ULK1 antibody
- Catalogue No.
- FNab09251
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- unc-51-like kinase 1(C. elegans)
- Alternative Names
- Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog (ATG1 antibody, hATG1)|Unc-51-like kinase 1|ULK1|KIAA0722 antibody
- UniProt ID
- O75385
- Observed MW
- 150 kDa
Application
- Tested Applications
- ELISA, WB,IHC
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:50-1:500
Validated Images
rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab09251(ULK1 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab09251(ULK1 Antibody) at dilution of 1:200
- Background
- ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).
