mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab09241(UGT2B7 Antibody) at dilution of 1:1000
IP Result of anti-UGT2B7 (IP:FNab09241, 4ug; Detection:FNab09241 1:800) with mouse liver tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human liver using FNab09241(UGT2B7 antibody) at dilution of 1:100
Background
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Its unique specificity for 3,4-catechol estrogens and estriol suggests it may play an important role in regulating the level and activity of these potent and active estrogen metabolites. Is also active with androsterone, hyodeoxycholic acid and tetrachlorocatechol(in vitro).