Products
UBXN1 antibody
- Product Name
- UBXN1 antibody
- Catalogue No.
- FNab09214
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- UBX domain protein 1
- Alternative Names
- 2B28 antibody, LOC51035 antibody, SAKS1 antibody, SAPK substrate protein 1 antibody, UBA/UBX 33.3 kDa protein antibody, UBX domain protein 1 antibody, UBXD10 antibody, UBXN1 antibody
- UniProt ID
- Q04323
- Observed MW
- 45 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab09214(UBXN1 antibody) at dilution of 1:500
- Background
- Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
