Products
UBASH3A-Specific antibody
- Product Name
- UBASH3A-Specific antibody
- Catalogue No.
- FNab09150
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin associated and SH3 domain containing, A
- Alternative Names
- Cbl interacting protein 4 antibody, CLIP4 antibody, STS 2 antibody, STS2 antibody, T cell ubiquitin ligand antibody, TULA antibody, UBASH3A antibody
- UniProt ID
- P57075
- Observed MW
- 69 kDa
Application
- Tested Applications
- ELISA, WB, IF, IP
- Recommended dilution
- WB: 1:200-1:2000; IF: 1:10-1:100；IP: 1:200-1:2000
Validated Images
human spleen tissue were subjected to SDS PAGE followed by western blot with FNab09150(UBASH3A-Specific antibody) at dilution of 1:400
IP Result of anti-UBASH3A-Specific (IP:FNab09150, 4ug; Detection:FNab09150 1:500) with mouse spleen tissue lysate 4000ug.
- Background
- UBASH3A gene encodes ubiquitin-associated and SH3 domain-containing protein A(UBASH3A) also known as T-cell ubiquitin ligand 1(TULA1) which is one of two family members belonging to the T-cell ubiquitin ligand(TULA) family. UBASH3A gene expression is limited to only a few tissues, with its highest expression in spleen, peripheral blood leukocytes, and bone marrow. UBASH3A protein is associated with c-Cbl and ubiquitylated proteins and has been implicated in the regulation of signaling mediated by protein-tyrosine kinases oth family members can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells via its interaction with apoptosis-inducing factor(AIF). This antibody is UBASH3A-specific.
