Products
TWSG1 antibody
- Product Name
- TWSG1 antibody
- Catalogue No.
- FNab09120
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- twisted gastrulation homolog 1
- Alternative Names
- TSG antibody, TWSG1 antibody
- UniProt ID
- Q9GZX9
- Observed MW
- 35 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab09120(TWSG1 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab09120(TWSG1 Antibody) at dilution of 1:50
- Background
- May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development(By similarity).
