Products
TWIST2 antibody
- Product Name
- TWIST2 antibody
- Catalogue No.
- FNab09119
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- twist homolog 2
- Alternative Names
- BHLHa39 antibody, Dermis expressed protein 1 antibody, Dermo 1 antibody, DERMO1 antibody, twist homolog 2(Drosophila) antibody, Twist related protein 2 antibody, TWIST2 antibody
- UniProt ID
- Q8WVJ9
- Observed MW
- 21 kDa, 65 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:2000
Validated Images
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab09119(TWIST2 antibody) at dilution of 1:1000
- Background
- Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism(By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
