MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with FNab09118(TWIST1 Antibody) at dilution of 1:600
IP Result of anti-TWIST1-specific (IP:FNab09118, 4ug; Detection:FNab09118 1:500) with MDA-MB-453s cells lysate 920ug.
Background
Twist-related protein 1(TWIST1), also named as BHLHA38, is 202 amino acid protein, which contains one bHLH domain. TWIST1 localizes in the nucleus and acts as a transcriptional regulator. TWIST1 inhibits monogenesis by sequestrating E proteins and inhibits tans-activation by MEF2. TWIST1 is expressed in subset of mesodermal cells. The antibody reacts specifically with twist1 protein.