TULP3 antibody

Synonyms:Tubby like protein 3 antibody, Tubby related protein 3 antibody, TUBL3 antibody, TULP3 antibody
Catalogue No.:FNab09109Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TULP3 antibody
Catalogue No.
FNab09109
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
tubby like protein 3
Alternative Names
Tubby like protein 3 antibody, Tubby related protein 3 antibody, TUBL3 antibody, TULP3 antibody
UniProt ID
O75386
Observed MW
56 kDa
Application
Tested Applications
ELISA, WB, IHC, IP, IF
Recommended dilution
WB: 1:500-1:1000; IHC: 1:20-1:200; IP: 1:200-1:1000; IF: 1:20-1:200
Validated Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab09109(TULP3 antibody) at dilution of 1:800
IP Result of anti-TULP3 (IP:FNab09109, 4ug; Detection:FNab09109 1:800) with SH-SY5Y cells lysate 1600ug.
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab09109(TULP3 antibody) at dilution of 1:100
Background
Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A(IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide(phosphoinositide) lipids. Both IFT-A-and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.