Products
TTF1 antibody
- Product Name
- TTF1 antibody
- Catalogue No.
- FNab09091
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- NK2 homeobox 1
- Alternative Names
- BHC antibody, Homeobox protein Nkx 2.1 antibody, NK 2 antibody, NK2 homeobox 1 antibody, NKX2 1 antibody, NKX2.1 antibody, NKX2-1 antibody, NKX2A antibody, TEBP antibody, Thyroid nuclear factor 1 antibody, Thyroid transcription factor 1 antibody, TITF1 antibody, TTF 1 antibody, TTF1 antibody
- UniProt ID
- P43699
- Observed MW
- 42 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09091(TFF1 antibody) at dilution of 1:1000
- Background
- NKX2-1, also named as NKX2A, TITF1 and TTF1, belongs to the NK-2 homeobox family. It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype. It may play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea(BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress(CHNRD). The antibody is specific to NKX2-1.
