Products

anti- TRIM6 antibody

FNab08991 Catalogue No.
Synonyms
RING finger protein 89, RNF89, TRIM6, tripartite motif containing 6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, IHC, WB
Product Information
Product Name
anti- TRIM6 antibody
Catalogue No.
FNab08991
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells(By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response(PubMed:24882218).
Immunogen Information
Immunogen
tripartite motif-containing 6
Synonyms
RING finger protein 89, RNF89, TRIM6, tripartite motif containing 6
Observed MW
56 kDa
Application
Tested Application
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Uniprot information
UniProt ID
Q9C030
Images
Immunohistochemistry of paraffin-embedded human colon cancer using FNab08991(TRIM6 antibody) at dilution of 1:50
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08991(TRIM6 Antibody) at dilution of 1:1000