HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08980(TRIM32 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lymphoma using FNab08980(TRIM32 antibody) at dilution of 1:50
Background
Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1(dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.