Products

TRIAP1 antibody

Synonyms:15E1.1 antibody, HSPC132 antibody, P53CSV antibody, Protein 15E1.1 antibody, TRIAP1 antibody, WF 1 antibody
Catalogue No.:FNab08964Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TRIAP1 antibody
Catalogue No.
FNab08964
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
TP53 regulated inhibitor of apoptosis 1
Alternative Names
15E1.1 antibody, HSPC132 antibody, P53CSV antibody, Protein 15E1.1 antibody, TRIAP1 antibody, WF 1 antibody
UniProt ID
O43715
Observed MW
32 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:5000
Validated Images
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08964(TRIAP1 Antibody) at dilution of 1:1000
Background
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).