Products
TRBP antibody
- Product Name
- TRBP antibody
- Catalogue No.
- FNab08956
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- TAR(HIV-1) RNA binding protein 2
- Alternative Names
- LOQS antibody, TAR RNA binding protein 2 antibody, TARBP2 antibody, TRBP antibody, TRBP1 antibody, TRBP2 antibody
- UniProt ID
- Q15633
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08956(TRBP antibody) at dilution of 1:1000
IP Result of anti-TRBP (IP:FNab08956, 4ug; Detection:FNab08956 1:1500) with mouse liver tissue lysate 6400ug.
Immunohistochemistry of paraffin-embedded human brain using FNab08956(TRBP antibody) at dilution of 1:100
- Background
- TARBP2 is a component of the RISC loading complex(RLC), also known as the micro-RNA(miRNA) loading complex(miRLC). Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs(pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs(siRNAs) from double-stranded RNA(dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat(LTR) of HIV-1, and stimulates translation of TAR-containing RNAs.
