HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08943(TRAPB, SSR2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab08943(TRAPB, SSR2 antibody) at dilution of 1:50
Background
TRAPB(translocon-associated protein subunit beta), also known as SSR2(signal sequence receptor subunit beta), is a 22-kDa single-spanning membrane glycoprotein of the endoplasmic reticulum(ER)(PMID: 7789174). It is a part of the tetrameric TRAP complex(TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma) which functions in regulating the retention of ER resident proteins(PMID: 7916687). The TRAP complex is also involved in endoplasmic reticulum-associated degradation(ERAD)(PMID: 17380188).