TRAPB/SSR2 antibody

Synonyms:DKFZp686F19123 antibody, HSD25 antibody, SSR beta antibody, SSR2 antibody, TLAP antibody, TRAP BETA antibody, TRAPB antibody
Catalogue No.:FNab08943Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, FC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TRAPB/SSR2 antibody
Catalogue No.
FNab08943
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
signal sequence receptor, beta(translocon-associated protein beta)
Alternative Names
DKFZp686F19123 antibody, HSD25 antibody, SSR beta antibody, SSR2 antibody, TLAP antibody, TRAP BETA antibody, TRAPB antibody
UniProt ID
P43308
Observed MW
24 kDa
Application
Tested Applications
ELISA, WB, IHC, FC, IF
Recommended dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08943(TRAPB, SSR2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab08943(TRAPB, SSR2 antibody) at dilution of 1:50
Background
TRAPB(translocon-associated protein subunit beta), also known as SSR2(signal sequence receptor subunit beta), is a 22-kDa single-spanning membrane glycoprotein of the endoplasmic reticulum(ER)(PMID: 7789174). It is a part of the tetrameric TRAP complex(TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma) which functions in regulating the retention of ER resident proteins(PMID: 7916687). The TRAP complex is also involved in endoplasmic reticulum-associated degradation(ERAD)(PMID: 17380188).