Products
transgelin/SM22 antibody
- Product Name
- transgelin/SM22 antibody
- Catalogue No.
- FNab08935
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 4B8
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transgelin
- Alternative Names
- SM22 antibody, SM22 alpha antibody, SM22a antibody, SM22alpha antibody, Smooth muscle protein 22 alpha antibody, TAGLN antibody, TAGLN1 antibody, transgelin antibody, TRANSGELIN 1 antibody
- UniProt ID
- Q01995
- Observed MW
- 22 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000-1:10000; IHC: 1:20-1:400
Validated Images
human colon tissue were subjected to SDS PAGE followed by western blot with FNab08935(TAGLN Antibody) at dilution of 1:4000
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab08935(TAGLN Antibody) at dilution of 1:200
- Background
- The transgelin family is a group of proteins that belong to 22kd actin-related calponin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells. This antibody was generated against full length transgelin 1 protein. It can cross-react with other two transgelins based on the sequence similarity.
