Products
transcription termination factor-Specific antibody
- Product Name
- transcription termination factor-Specific antibody
- Catalogue No.
- FNab08928
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 7C4
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transcription termination factor, RNA polymerase I
- Alternative Names
- RNA polymerase I termination factor antibody, Transcription termination factor I antibody, TFF1 antibody, TFF-I antibody
- UniProt ID
- Q15361
- Observed MW
- 43 kDa, 66 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:1000-1:10000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08928(TTF1-Specific antibody) at dilution of 1:2000
- Background
- TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1.
