Products
TRAF3IP1 antibody
- Product Name
- TRAF3IP1 antibody
- Catalogue No.
- FNab08918
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- TNF receptor-associated factor 3 interacting protein 1
- Alternative Names
- IFT54 antibody, MIPT3 antibody
- UniProt ID
- Q8TDR0
- Observed MW
- 83 kDa
Application
- Tested Applications
- ELISA, IP, WB, IF, IHC
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08918(TRAF3IP1 Antibody) at dilution of 1:300
IP Result of anti-TRAF3IP1 (IP:FNab08918, 3ug; Detection:FNab08918 1:300) with HeLa cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08918(TRAF3IP1 Antibody) at dilution of 1:50
- Background
- Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels(PubMed:26487268). Involved in ciliogenesis(By similarity).
