TPSAB1 antibody

Synonyms:MCP7 antibody, TPS1 antibody, TPS2 antibody, TPSAB1 antibody, TPSB1 antibody, Tryptase 1 antibody, tryptase alpha/beta 1 antibody, Tryptase beta 1 antibody, Tryptase I antibody
Catalogue No.:FNab08904Reactivity:Human
Host:MouseTested Application:ELISA, IHC, WB
Clonality:monoclonalIsotype:IgG1
  • SPECIFICATIONS
Product Name
TPSAB1 antibody
Catalogue No.
FNab08904
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG1
Clone ID
9D8
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
tryptase alpha/beta 1
Alternative Names
MCP7 antibody, TPS1 antibody, TPS2 antibody, TPSAB1 antibody, TPSB1 antibody, Tryptase 1 antibody, tryptase alpha/beta 1 antibody, Tryptase beta 1 antibody, Tryptase I antibody
UniProt ID
Q15661
Observed MW
31 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab08904(TPSAB1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab08904(TPSAB1 Antibody) at dilution of 1:500. Heat mediated antigen retrieved with Citric acid buffer, pH6.0
Background
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates(PubMed:18854315).