human kidney tissue were subjected to SDS PAGE followed by western blot with FNab08904(TPSAB1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab08904(TPSAB1 Antibody) at dilution of 1:500. Heat mediated antigen retrieved with Citric acid buffer, pH6.0
Background
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates(PubMed:18854315).