TPSAB1 antibody

Synonyms:MCP7 antibody, TPS1 antibody, TPS2 antibody, TPSAB1 antibody, TPSB1 antibody, Tryptase 1 antibody, tryptase alpha/beta 1 antibody, Tryptase beta 1 antibody, Tryptase I antibody
Catalogue No.:FNab08903Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TPSAB1 antibody
Catalogue No.
FNab08903
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
tryptase alpha/beta 1
Alternative Names
MCP7 antibody, TPS1 antibody, TPS2 antibody, TPSAB1 antibody, TPSB1 antibody, Tryptase 1 antibody, tryptase alpha/beta 1 antibody, Tryptase beta 1 antibody, Tryptase I antibody
UniProt ID
Q15661
Observed MW
32-38 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab08903(TPSAB1 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human appendix using FNab08903(TPSAB1 antibody) at dilution of 1:100
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HepG2 cells using FNab08903 ( TPSAB1 Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Background
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates(PubMed:18854315).