Products
TNFR1 antibody
- Product Name
- TNFR1 antibody
- Catalogue No.
- FNab08823
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 1G4
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tumor necrosis factor receptor superfamily, member 1A
- Alternative Names
- CD120a antibody, FPF antibody, p55 antibody, p55 R antibody, p60 antibody, TBP1 antibody, TBPI antibody, TNF R antibody, TNF R I antibody, TNF R1 antibody, TNF R55 antibody, TNF Receptor 1 antibody, TNF Receptor I antibody, TNF RI antibody, TNFAR antibody, TNFR I antibody, TNFR1 antibody, TNFR55 antibody, TNFR60 antibody, TNFRSF1A antibody
- UniProt ID
- P19438
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB,IHC, FC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:50-1:500
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab08823(TNFR1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab08823(TNFR1 Antibody) at dilution of 1:200
- Background
- Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases(aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
