A549 cells were subjected to SDS PAGE followed by western blot with FNab08819(TNFAIP8 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human tonsillitis slide using FNab08819(TNFAIP8 Antibody) at dilution of 1:50
Background
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.