Products
TNFAIP1 antibody
- Product Name
- TNFAIP1 antibody
- Catalogue No.
- FNab08817
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 2H3
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tumor necrosis factor, alpha-induced protein 1(endothelial)
- Alternative Names
- BACURD2 antibody, EDP1 antibody
- UniProt ID
- Q13829
- Observed MW
- 36 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000-1:6000; IHC: 1:50-1:600
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08817(TNFAIP1 antibody) at dilution of 1:3000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab08817( TNFAIP1 antibody) at dilution of 1:300
- Background
- Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
