Products
TMPRSS2 antibody
- Product Name
- TMPRSS2 antibody
- Catalogue No.
- FNab08804
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transmembrane protease, serine 2
- Alternative Names
- PRSS10 antibody
- UniProt ID
- O15393
- Observed MW
- 52 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
22Rv1 cells were subjected to SDS PAGE followed by western blot with FNab08804(TMPRSS2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach cancer using FNab08804(TMPRSS2 Antibody) at dilution of 1:200
- Background
- This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
