HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08760(TMEM175 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded mouse brain using FNab08760(TMEM175 antibody) at dilution of 1:100
Background
Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.