mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08744(TMEM106B antibody) at dilution of 1:2000
IP Result of anti-TMEM106B (IP:FNab08744, 3ug; Detection:FNab08744 1:1000) with mouse brain tissue lysate 6000ug.
Immunohistochemistry of paraffin-embedded human brain using FNab08744(TMEM106B antibody) at dilution of 1:100
Background
Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.