TLR7 antibody

Category: Research Area:
Synonyms：TLR7 antibody, toll like receptor 7 antibody
Catalogue No.：FNab08730Reactivity：Human, Mouse, Rat
Host：RabbitTested Application：ELISA, WB, IHC
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
TLR7 antibody
Catalogue No.
FNab08730
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
toll-like receptor 7
Alternative Names
TLR7 antibody, toll like receptor 7 antibody
UniProt ID
Q9NYK1
Observed MW
121kd
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:200-1:600; IHC: 1:20-1:200
Validated Images
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab08730(TLR7 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab08730(TLR7 Antibody) at dilution of 1:50
Background
Key component of innate and adaptive immunity. TLRs(Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(By similarity).
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