Products

anti- TIA1 antibody

FNab08685 Catalogue No.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC, IF
Product Information
Product Name
anti- TIA1 antibody
Catalogue No.
FNab08685
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Immunogen Information
Immunogen
TIA1 cytotoxic granule-associated RNA binding protein
Observed MW
54 kDa
Application
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:100
Uniprot information
UniProt ID
P31483
Images
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08685 (TIA1 antibody) at dilution of 1:100
BT-474 cells were subjected to SDS PAGE followed by western blot with FNab08685 (TIA1 antibody) at dilution of 1:1000