Products
THEM4 antibody
- Product Name
- THEM4 antibody
- Catalogue No.
- FNab08663
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- thioesterase superfamily member 4
- Alternative Names
- CTMP antibody
- UniProt ID
- Q5T1C6
- Observed MW
- 26 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08663(THEM4 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab08663(THEM4 antibody) at dilution of 1:50
- Background
- Has acyl-CoA thioesterase activity towards medium and long-chain(C14 to C18) fatty acyl-CoA substrates, and probably plays an role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
