Products
TFIP11 antibody
- Product Name
- TFIP11 antibody
- Catalogue No.
- FNab08633
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 3H5
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tuftelin interacting protein 11
- Alternative Names
- STIP antibody
- UniProt ID
- Q9UBB9
- Observed MW
- 97 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:50-1:500
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08633(TFIP11 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using FNab08633(TFIP11 Antibody) at dilution of 1:50
- Background
- Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large(IL) and Intron Small(IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
