Products
TFEC antibody
- Product Name
- TFEC antibody
- Catalogue No.
- FNab08628
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transcription factor EC
- Alternative Names
- BHLHE34 antibody, TCFEC antibody, TFECL antibody
- UniProt ID
- O14948
- Observed MW
- 65 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08628(TFEC antibody) at dilution of 1:300
IP Result of anti-TFEC (IP:FNab08628, 4ug; Detection:FNab08628 1:500) with mouse testis tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human colon cancer using FNab08628(TFEC antibody) at dilution of 1:100
- Background
- Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F(that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase(TRAP) E-box containing promoter(By similarity). Collaborates with MITF in target gene activation(By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence(By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer(By similarity). Binds DNA in a homo-or heterodimeric form.
