Products
TFAP2B antibody
- Product Name
- TFAP2B antibody
- Catalogue No.
- FNab08618
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transcription factor AP-2 beta(activating enhancer binding protein 2 beta)
- UniProt ID
- Q92481
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab08618(TFAP2B antibody) at dilution of 1:800
IP Result of anti-TFAP2B (IP:FNab08618, 4ug; Detection:FNab08618 1:500) with MCF-7 cells lysate 800ug.
- Background
- Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
